Research

  • The Abate-Shen Lab focuses on prostate and bladder cancer and encompasses mechanism-based studies, analyses of genetically-engineered mouse models, and state-of-the-art systems biology approaches.

  • The Colecraft Lab is currently focused on the development of novel genetically-encoded ion channel modulators, Ion channelopathies, and Molecular physiology of voltage-gated Ca2+ channels.

  • The Fan Lab studies the molecular mechanisms by which G protein-coupled receptors (GPCRs) transmit signals across biological membranes.

  • The Harrison Lab's main area of research interest is in synaptic transmission, especially at inhibitory synapses, which are necessary for the normal processing of information in the mammalian brain.

  • The research in the Hen Lab is focused on the contribution of serotonin (5-HT) receptors to pathological states such as depression and anxiety.

  • The Ju Laboratory focuses on the design and synthesis of novel molecules for biological engineering, imaging, and the development of new technologies for genomic research.

  • The Kass Lab is focused on understanding the molecular physiology and pharmacology of congenital arrhythmias.

  • The Kellendonk laboratory uses mouse genetic tools in an effort to understand the biology that underlies cognitive symptoms of schizophrenia.

  • The Marx Lab studies the regulation of ion channels by macromolecular complexes.

  • The Miller Lab focuses on disruption of neurotransmitter storage and the loss of dopamine neurons in Parkinson's disease, and role of environmental factors in disease development.

  • The Prince Lab studies the interaction of the host and bacterial pathogens in both the airway and skin.

  • The Sieglebaum Lab is leading efforts to understand how electrical signals in the brain encode memories that can last a lifetime, and how changes to these signals play a role in psychiatric disorders.

  • The Steinberg Lab focuses on the mechanisms that underlie the physiologically important changes in cardiomyocyte adrenergic receptor responsiveness.

  • The Sulzer lab studies the physiology and cell biology of neurotransmission, particularly of dopamine and the striatum, and mechanisms involved in both normal and diseased functions of these systems.

  • The Yan Lab focuses on the molecular and cellular mechanisms of cellular stress and survival in aging and neurodegenerative disorders relevant to Alzheimer’s disease and diabetes.

  • The Yazawa Lab uses interdisciplinary approaches to uncover the molecular mechanism underlying human genetic diseases and to develop new therapies.