Research

  • The Abate-Shen Lab focuses on prostate and bladder cancer and encompasses mechanism-based studies, analyses of genetically-engineered mouse models, and state-of-the-art systems biology approaches.

  • The Colecraft Lab is currently focused on the development of novel genetically-encoded ion channel modulators, Ion channelopathies, and Molecular physiology of voltage-gated Ca2+ channels.

  • Dr. Diano’s research focuses on intracellular nutrient sensing mechanisms in brain cells regulating energy and glucose metabolism, and how their derangement promotes development of metabolic disorders

  • The Fan Lab studies the molecular mechanisms by which G protein-coupled receptors (GPCRs) transmit signals across biological membranes.

  • The Harrison Lab's main area of research interest is in synaptic transmission, especially at inhibitory synapses, which are necessary for the normal processing of information in the mammalian brain.

  • The research in the Hen Lab is focused on the contribution of serotonin (5-HT) receptors to pathological states such as depression and anxiety.

  • The Ju Laboratory focuses on the design and synthesis of novel molecules for biological engineering, imaging, and the development of new technologies for genomic research.

  • The Kass Lab is focused on understanding the molecular physiology and pharmacology of congenital arrhythmias.

  • The Kellendonk laboratory uses mouse genetic tools in an effort to understand the biology that underlies cognitive symptoms of schizophrenia.

  • The Marx Lab studies the regulation of ion channels by macromolecular complexes.

  • The Miller Lab focuses on disruption of neurotransmitter storage and the loss of dopamine neurons in Parkinson's disease, and role of environmental factors in disease development.

  • The Prince Lab studies the interaction of the host and bacterial pathogens in both the airway and skin.

  • The Sharma Lab focuses on the development and function of neural circuits that lead to pain.

  • The Sieglebaum Lab is leading efforts to understand how electrical signals in the brain encode memories that can last a lifetime, and how changes to these signals play a role in psychiatric disorders.

  • The Steinberg Lab focuses on the mechanisms that underlie the physiologically important changes in cardiomyocyte adrenergic receptor responsiveness.

  • The Sulzer Lab studies the physiology and cell biology of neurotransmission, particularly with dopamine and the striatum, and mechanisms involved in both normal and diseased functions of these systems

    Microscope image with fluorescent treatment
  • The Yan Lab focuses on the molecular and cellular mechanisms of cellular stress and survival in aging and neurodegenerative disorders relevant to Alzheimer’s disease and diabetes.

  • The Yazawa Lab uses interdisciplinary approaches to uncover the molecular mechanism underlying human genetic diseases and to develop new therapies.